I have multiple IP's on our new exchange 2010 box, but I need it to only send on IP #1. It appears to just route them randomly, I'm wondering how I go about telling exchange that I want it to route on only ONE ip address.
You're looking for the "Set-SendConnector" cmdlet. Execute the command below from an Exchange Management Shell:
By default, the SourceIPAddress is set to 0.0.0.0, which corresponds to all IP addreses on the machine. Scoping it down to a single IP address will get you what you want.