When I try to send an email from my blackberry to the same address, exchange denies the message with 5.5.4 5.1.0 Sender Denied.

Any ideas?

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Are you using a BES server? – joeqwerty Jan 18 '10 at 20:19
EDIT: beaten by joeqwerty – DanBig Jan 18 '10 at 20:23
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You should configure authentication for sending out e-mails. I am not a blackberry user but definitely this is an authentication issue which will be the same as with any other email clients. In your email accounts settings check the outgoing mail options.

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