I've just installed PHP (5.3.1) and MySQL (5.1.44) on my development machine. Then I used the Web Platform Installer to install a copy of Joomla and Drupal.
However, when I tried to browse either site application, I get a HTTP Error 500:
Module FastCgiModule Notification ExecuteRequestHandler Handler PHP_via_FastCGI Error Code 0x00000000 Requested URL http://localhost:808/drupal/index.php Physical Path D:\Projects\drupal\index.php Logon Method Anonymous Logon User Anonymous
PHPInfo.php reports that FastCGI is configured (not sure if that is significant). Sure the fact that PHPInfo.php reports anything is perhaps an indication that PHP itself is working...?
I'm struggling to know where to look for a solution... Each application appears to be configure similarly to my other [ASP/ASP.NET] applications.