We have a SQL server running SQL 2005 Workgroup 64 bit (9.0.4273), on Windows 2003 server 64 bit.
We have run sp_configure and reconfigured the server which indicates that the clr is now enabled.
exec sp_configure 'clr enabled', '1' go reconfigure go
However, when trying to call CREATE ASSEMBLY the server completely dies on us and we have to do a full reboot of the machine.
A little more diagnostic information, even though clr enabled is set to 1 and we have rebooted the full server, running the following statement
select * from sys.dm_clr_properties
directory version state locked CLR version with mscoree
which is what it says when the CLR is not enabled on another machine.
On a correctly enabled machine (after reboot) this function reads
directory C:\Windows\Microsoft.NET\Framework64\v2.0.50727\ version v2.0.50727 state CLR is initialized