I think this mostly happens when trying to open files opened by other users. In the XP/2003 days you would get some kind of warning about a locked/read only file. With 7/Vista/2008 I'm just seeing clients hang (Word just sits there) and if I go into the file share and attempt to right-click on the file, explorer hangs for several minutes.
I tried disabling AV on the file server as well as locally. No luck.
I've read that SMB2.0 might be the culprit here, but even testing that solution means disabling it on both the client and server, and requires a server reboot. Does this sound like an SMB2 issue?
The server is 2008 SP1. The clients are Win7 vanilla and Vista SP2 with all the current updates. Office 2007 SP2 with all updates. Thanks.