We would like to prevent USB access to machines (primarily Windows XP, 2003 machines) so that it would not be possible for employees to copy anything from the disk to a pen drive.

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You can do this using Group Policy Preferences.

See here for more info.

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it works, thanks – user42891 Jul 29 '10 at 12:50
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You can disable USB ports in Device Manager, but it will affect administrators as well.

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thats fine with us – user42891 May 12 '10 at 9:22
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At my current job, we use Lumension Endpoint Security (http://www.lumension.com/). It is annoying as hell, which is exactly what it is supposed to do, so yes, it works well.

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I would have said disabling USB ports too, but bear in tmind if your mouse/keyboard/webcam are usb this will disable them too.

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i don't want my other devices to get affected with this, thanks for the hint – user42891 May 21 '10 at 13:31
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I used devicelock in the past, it does the job but it was a bit tricky to setup and maintein

http://www.devicelock.com/dl/

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Microsoft provides an Administrative template to restrict USB drives on 2003/XP machines. To make the administrative template available in Group Policy Management, you will need to paste the administrative template text into a "RestrictDrives.adm" file, save it, and follow the instructions under the links in the "More Information" section.

http://support.microsoft.com/kb/555324

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