Currently using Vembu's storegrid. Not very happy with the user interface, the reports or nothing. Very hard to get a good grip on how well everything is.
backing up typical servers such as Windows 2003/2008, multiple Linux flavors, exchange, MS SQL, MySQL etc etc.
Recently we also have an interest in providing small companies backup of their office machines, so either two different solutions or one that is suitable for both.
We obviously need both full and incremental backups.
We do backup to DAS (Direct Attached Storage).
What do you guys use?