When tuning a web site/service for performance, is there a downside to using a less common top-level domain (e.g. 'nu', 'tv', 'io') for your hostnames? My concern is that if you're using a TLD assigned to a specific country, then initial DNS lookups will somehow involve network resources in or near that country. Or are all TLDs pretty much location-independent, logically?
If you'd care to comment on other potential issues in using non-standard TLDs, I'd be interested in that too. Thanks!