I have several Centos 5 web hosting servers with local instances of MySQL that I am looking to segment so that all servers connect to a central MySQL instance. These are web applications doing more reads than writes, and I would like to keep the databases available as much as possible while also keeping the host servers updated. I've been reading the docs at http://dev.mysql.com/doc/refman/5.0/en/ha-overview.html which are informative, but I'd like to know what others have done in practice that have worked for them.

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Multi-Master Replication Manager for MySQL is good. http://mysql-mmm.org/

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