what are the functional differences between these guys?

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Why the votedown? .profile vs .bashrc confusion is one of the most common things I see from even experienced Unix/Linux users. – geekosaur Apr 20 '11 at 15:57
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.bash_profile and .bashrc are specific to bash, whereas .profile is read by many shells in the absence of their own shell-specific config files. (.profile was used by the original Bourne shell.) .bash_profile or .profile is read by login shells, along with .bashrc; subshells read only .bashrc. (Between job control and modern windowing systems, .bashrc by itself doesn't get used much. If you use screen or tmux, screens/windows usually run subshells instead of login shells.)

The idea behind this was that one-time setup was done by .profile (or shell-specific version thereof), and per-shell stuff by .bashrc. For example, you generally only want to load environment variables once per session instead of getting them whacked any time you launch a subshell within a session, whereas you always want your aliases (which aren't propagated automatically like environment variables are).

Other notable shell config files:

/etc/bash_profile (fallback /etc/profile) is read before the user's .profile for system-wide configuration, and likewise /etc/bashrc in subshells (no fallback for this one). Many systems including Ubuntu also use an /etc/profile.d directory containing shell scriptlets, which are . (source)-ed from /etc/profile; the fragments here are per-shell, with *.sh applying to all Bourne/POSIX compatible shells and other extensions applying to that particular shell.

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According to the bash man page, .bash_profile is executed for login shells, while .bashrc is executed for interactive non-login shells.

So, what is a login or non-login shell?

When you login (type username and password) via console, either sitting at the machine, or remotely via ssh: .bash_profile is executed to configure your shell before the initial command prompt. But, if you’ve already logged into your machine and open a new terminal window (xterm) inside Gnome or KDE, then .bashrc is executed before the window command prompt. .bashrc is also run when you start a new bash instance by typing /bin/bash in a terminal.

An exception to the terminal window guidelines is Mac OS X’s Terminal.app, which runs a login shell by default for each new terminal window, calling .bash_profile instead of .bashrc. Other GUI terminal emulators may do the same, but most tend not to.

More here http://www.joshstaiger.org/archives/2005/07/bash_profile_vs.html

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