Disclaimer: I'm not an expert on either Linux, Nginx, Varnish or anything related to servers but I've managed to get a Linode VPS up and running, serving two blogs with Wordpress on them to different domains. However;
The sites are basically just copies of other setups and nothing that I've done myself, so I wanted to try things out for myself. Tried Apache, tried Nginx with Wordpress and W3 Total Cache and APC. I love optimization, and was curious if running Nginx and Varnish together would yield better results than just Nginx? This is with a Wordpress site with APC and W3 Total Cache.
Or would just running Nginx as a reverse proxy with Varnish caching with Apache as the backend (as I understood it at least, might be wrong) overall the best solution?
Any input is greatly appreciated. Thanks!