Exchange 2007, Outlook 2010 Error when setting Out Of Office (Automatic Replies) from Outlook: Your automatic reply settings cannot be displayed because the server is currently unavailable. Try again later.

Setting this through OWA works fine.

Autodiscover is working, and all addresses are resolvable through DNS. Outlook profile created from scratch. Anonymous access disabled for EWS/OWA (IIS on Exchange box).

I'm out of steam for troubleshooting. Any ideas?

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While I can't be sure which update fixed it, I did run a series of Windows Updates, and after a reboot this issue went away. – derjur Dec 30 '11 at 14:05
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Is this when you are changing the responder for a different account than the one you are logged into? if not then this link has a series of steps on how to troubleshoot the message you are getting. Please try them all and report back

out of office troubleshooting

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