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Are there any Linux distributions that are intended exclusivity for running windows programs under WINE?

My particular use case is that I have a windows program that I'd like to install in a VM (I'd rather not install it on any of my system) but I don't want to go through the hassle of setting up windows in a VM (last time I tried, it didn't work for some reason and I don't feel like debugging it).

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closed as off topic by Shane Madden, Chopper3, gWaldo, ThatGraemeGuy, MDMarra Jul 23 '12 at 11:00

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According to the Wine forums, there is no one favored Linux distribution. For optimal stability and performance, you are definitely well-advised to invest in the commercial version of wine (CrossOver). They optimize builds for a short list of specific popular Windows applications.

With that said, I have always had the best luck with a combination of Ubuntu and Wine. The abundance of users results in lots of excellent bug reports from which the Wine team benefits greatly. If it's not a niche program, it's also almost guaranteed that someone else has tried your software with Wine on Ubuntu.

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