We have Windows 2008R2 with Exchange 2010. A user logged in and they receive a message
The User Profile Service Failed the Logon. User Profile Cannot Be Loaded.
I can currently remote in as I have had a profile on there for a while now, but it is stopping anyone creating a new profile.
I have checked the registry HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows NT\CurrentVersion\ProfileList but there does not seem anything out of the norm, not .bak file etc.
I have also restarted the Server and applied updates.