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I have a plesk 10.2 shared hosting running IIS 7. Trying to run .Net 4.0 website. It gives following error :

HTTP Error 500.23 - Internal Server Error
An ASP.NET setting has been detected that does not apply in 
Integrated managed pipeline mode.

Found this link

But could not found Handler Mappings section in control panel.

Any solution??

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You can find the answer here:

Which is: Make sure to add this to your web.config

    <validation validateIntegratedModeConfiguration="false"/>
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This also happened to us migrating from Parallels Plesk legacy to Parallels Plesk PPA and adding this setting sorted it out. – Eugene van der Merwe Nov 11 '13 at 10:06

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