My server hosts several sites. All of them are fine except for one with a subdomain.domain.com/ip binding. Attempting to access it just times out. When attempting to access it via the ip I would expect to simple get the IIS 7 log page, but that also times out. When access from the server, the site works just fine.
I've had this come up previously and a restart fixed it, but I can't restart that machine during the work day. I tried restarting just IIS, but no change. Any thoughts?
So the issue turned out to be that the subnet mask for the site was being changed from 255.255.255.224 to 255.255.255.255. It reoccurred several times and would often affect multiple ip addresses. At one point, all of them changed. We kept resetting to the correct subnet mask when this occurred and it now appears to have stopped the behavior. However, I don't know what would have cause this to happen in the first place.