Is there a setting in IIS 7.5 to default the "Enable 32-Bit Applications" to False on newly created app pools? I know how to set it for one app pool in power shell, but I'm wondering if there's a global IIS setting for this so it will always be false when a new one is created. Thanks!
The default value for "Enable 32-Bit Applications" is "False" by default. If that is not the case in your setup, you can "fix" it using any of these methods:
Using GUI tool:
IIS Manager | Application Pools | Right click | Set Application Pool Defaults...
Using command line (appcmd.exe in this particular case):