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We have a Database sever running Microsoft Reporting Services on our network. The users with browser permissions on the server come from our AD Domain, and from a second AD Domain we share trust with (our sister office connecting to us through a VPN.)

Periodically, all the users from the second AD Domain will just drop from the server. When this happens, we cannot readd the users unless we reboot the server. Since this is a production server this can be difficult at times to arrange.

Not being a network admin, I am unsure as to what could be the cause of this problem or how to go about diagnosing it. Any assistance will be helpful.

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Just a suggestion but you should accept some of your open questions. Your accept rate is currently 20% which does not entice people to answer questions for you. –  Brent Pabst Aug 8 '12 at 19:06
    
Most of them didn't have answers, just healthy amounts of back and forth in the comments. But fair is fair, I went in and marked the ones I thought had a valid answer. –  Goblyn27 Aug 8 '12 at 23:08
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