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Can an application running on a VM access a physical COM port in order to communicate with a device plugged into it?

I have tried it in VirtualBox, and no joy. I wondered if enterprise virtualization solutions would allow it?

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up vote 4 down vote accepted

VMWare ESXi will allow you to connect a physical serial port to a guest VM.

Serial Port Configuration

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You are a gentleman. So, will that just show up as a COM port in my guest Windows OS? Can I choose the port number? – Black Knight Aug 20 '12 at 20:04

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