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How can I clear the cache of all settings and configurations for all of my Application Virtualization (App-V) applications?

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You can use the sftmime command to change and configure App-V packages, and applications.

To clear all settings and configurations for all of your App-V applications, run the following command from a command prompt:

sftmime clear obj:app

By default, sftmime is located in the following folder:

C:\Program Files\Microsoft Application Virtualization Client
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