I've got a Windows Server 2008 machine that is using an SMTP server with IIS 6. (I don't know the circumstances of that setup.) The machine itself uses IIS 7.
It quits working after like a day. I have to reboot the service daily just to get it to keep working.
I'm actually a UNIX guy, so I don't even know where to begin looking for where the failure is. Alternatively, does anyone have a solution? (The SMTP service sends out emails from websites.)