I'm running your standard Domain set up - AD with DNS and a RDS server.
On the RDS server, I've mapped some drives to a local NAS using the DNS shortname...
\\folders is a static DNS entry on the AD server.
"Randomly" it starts throwing the error "Windows cannot access \\folders"
nslookup folders (connects to local DNS server and returns the proper IP)
connect by ip address \\192.168.1.111\sharefolder
connect by FQDN \\folders.domain.com\sharedfolder
but I cannot use \\folders\sharedfolders again until I restart the RDS server.
net view \\folders = System error 53 has occured.
Thing is, I restarted the server Saturday afternoon for the problem and now it's Monday morning and right back to it!