Is there any difference in performance, optimisations in MSSQL 2012 on Opteron and Xeon platform ?
basically we are thinking about 2 x 6 Cores Xeon E5-1660 or 2 x 16 cores Opteron 6380
Unless you run an OLAP system the CPU is basically useless. Database servers are a LOT more likely to be limited by RAM and the disc subsystem. CPU is not a primary concern until you get REALLY big.