Is it possible to disable or reassign some or all of the built in Windows keyboard shortcuts? Are there any third party tools that make this task easy? Has the method to accomplish this task changed between Windows releases?
You should be able to set a registry entry for disabling hotkeys involving the "Windows" key.
Disable for All Users:
Disable for YOUR User:
Add a new DWORD (32-bit) Value named NoWinKeys
Set the value to "1" to disable and "0" to enable.
I would suggest this here: AutoHotKey
AutoHotkey unleashes the full potential of your keyboard, joystick, and mouse. For example, in addition to the typical Control, Alt, and Shift modifiers, you can use the Windows key and the Capslock key as modifiers. In fact, you can make any key or mouse button act as a modifier.
Also see here