I need to be able to do the following:
Boot from said disk delete all C:\documents and settings\jafdkjewi folders (Excepting All Users, Default User, and Select Few others) reboot
It's difficult to tell what is being asked here. This question is ambiguous, vague, incomplete, overly broad, or rhetorical and cannot be reasonably answered in its current form. For help clarifying this question so that it can be reopened, see the FAQ.
Windows PE or Bart PE should be able to do this, but why are you not deleting profiles in the usual, documented and accepted manner?
I am guessing you want to do this in order to clean old computers off for re-use?
If so, I recommend you clean one and take an image of the hard drive, then deploy using that. Assuming they are all the same model, this would be easy.
Otherwise mh has the best answer, but it will need some time for you to build it.