Running on small servers it would make sense offloading these as much as possible for performance. Also offloading will prevent from the server becoming a bottleneck. Therefore I use memcached for sessions, database indexes, user data etc.
Question; Would it be possible to connect my PHP (Zend) Opcache to Memcached-cluster?
Ultimately multiple server reusing the opcache from memcached? It would also make it possible to giantly increase my cache size?