/w00tw00t.at.ISC.SANS.DFind: is a very common request signature from the "Dfind" vulnerability scanner. The Dfind scanner appears to be something that gets installed on people's Windows boxes as malware or trojans, but it can be downloaded legitimately from a few sources (just Google it).
It's basically checking for holes in your security, so not quite a hack ATTEMPT, but it's the equivalent of someone casing the joint. That said, this is super common and relatively harmless as long as you have secured the rest of your site. You can block these requests easily using any combination of URL Rewriting, ACLs, Apache Directives, etc.
Any server you have running on PORT 80 on a public IP is likely to see this at some point.
If you are using phpmyadmin, you should probably secure it by using ACLs or some equivalent to prevent access from any IP not owned by you, change the directory alias so that it's a bit more obtuse, and/or only turn it on when you are needing to use it.
As a side-note, you can use MySQL's own MySQLAdministrator and MySQLQueryBrowser which do more and have a better interface, and in order to allow remote access to the server without exposing it to the world, setup a secure SSH tunnel. I wrote about how to do it on a blog if you are interested.