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I want to configure a separate SMTP send connector per user. Is this possible?


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This is not possible in Exchange. About the closest you can get is to use scoped connectors to limit routing of outbound email to the local site.

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See here:

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We really do prefer that answers have content, not pointers to content. This may theoretically answer the question however, it would be preferable to include the essential parts of the answer here, and provide the link for reference. – Iain Nov 22 '11 at 21:28

There are also 3rd party tools that allow this. Check out MultiSendcon. It distributes emails to different smtp relays / smarthost according to the sender.

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