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Block port 25 on SBS 2003; allow Exchange

I know this is a noob question, but I haven't been able to find an answer on exactly what I'm looking for. My mail server was recently blacklisted due to being infected with cutwail. Part of the ...
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What's the Purpose of Exchange Frontend Servers

What's the Purpose of Exchange Frontend Servers in this configuration? Config: SMB with single Exchange backend cluster. ISA server nodes with Published OWA/RPC/etc web sites. The cluster is located ...