I had a problem with an application running in Windows Server 2008 R2. I found from IBM's website that the reason for this problem was that the application was 32bit and Win Server 64 bit. The guidance was:

Method #2

Modify the 64-bit client device (for example Windows 2003 64-bit Citrix/Terminal Server) to automatically run all website's .NET code as 32 bit


  1. Logon to the 64-bit (operating system) client device as an administrator

  2. Start - Run "CMD" (to launch a command prompt)

  3. Change directory to C:\WINDOWS\Microsoft.NET\Framework64\v2.0.50727\
  4. Ldr64.exe setwow

This will disable the "COMPLUS_ENABLE_64BIT" flag and cause all .NET code to run as 32-bit on this 64-bit client device.

I would like to know how can I enable this COMPLUS_ENABLE_64BIT again?


You repeat the first three steps, then execute Ldr64 with different arguments:

Ldr64.exe Set64

This will restore the ability to run the 64bit runtime.

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