We currently use Adobe Reader XI in a Windows 7 environment and have been rolling out Nuance PowerPDF recently. Adobe Reader XI always remains the default however some websites have had issues- we've found the solution is to open Adobe Reader, select Edit -> Preference, General and click Select Default PDF Handler. This fixes our issue by running an installer and possibly correcting whatever files were modified by PowerPDF, even though PowerPDF was never set as the default.
The problem is we need to do this for over 900 users in multiple offices. Is there a command or automated way to run this process through group policy or SCCM? It runs what seems like an installer so it has to be this process, not as simple as just selecting a default file association.