I know that similar questions have been asked already, but I feel that they were on a rather theoretical level and are not quite applicable to my case.
We're operating 3 ESXi 6.0 hosts, all backed by the same HP EVA P6300 via FC. As proposed by the EVA P6300 Best Practice Guide (https://h41368.www4.hp.com/h41111/rfg_formprocessor/SWD_Installed_Base/pl/pl/pdf/TWP_4AA3-2641ENW.PDF), we've put all out 48 disks (600GB, 10k RPM) into the same Disk Group.
I like to use vRaid6 because I personally feel a bit uneasy when using a Raid0 over 6x Raid5s with 8 Disks each (which is essentially what EVA does with vRaid5).
Overall we have about 40 VMs, most of them (~35) with very little Disk I/Os, and a few (~5) with high Disk I/O spikes every couple of minutes (SQL servers / file servers).
For handling reasons, it would be easiest to just create one big LUN/Datastore. Given the fact that all LUNs we create would be backed by the same physical disks anyway, are there any performance implications when only having one LUN? Is there a point in having more than one LUN because of locking or I/O queues?
The HP Best Practice Guide states that one should "Follow operating system and application requirements for LUN count", but I couldn't find any information by VmWare regarding a recommended LUN count.
Thanks in advance for any insight!